A Critical Assessment of the Neurodestructive and Neuroprotective Effects of Nitric Oxide
Autor: | Zhi Zhang, Run-Sheng Ruan, Seng Kee Leong |
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Rok vydání: | 2002 |
Předmět: |
Neurons
business.industry General Neuroscience Nitric Oxide Neuroprotection General Biochemistry Genetics and Molecular Biology Nitric oxide chemistry.chemical_compound NG-Nitroarginine Methyl Ester Neuroprotective Agents History and Philosophy of Science chemistry Anesthesia Animals Humans Medicine Critical assessment Enzyme Inhibitors Nitric Oxide Synthase business Neuroscience |
Zdroj: | Annals of the New York Academy of Sciences. 962:161-181 |
ISSN: | 1749-6632 0077-8923 |
DOI: | 10.1111/j.1749-6632.2002.tb04066.x |
Popis: | Whether nitric oxide is cytodestructive or cytoprotective is of obvious clinical importance. The debate on this subject in the past decade has generated much “heat and light”. This paper focuses on the actions of NO on the nervous system and reexamines the controversial issue and the contribution of the authors and their colleagues in the light of recent findings. We also report new findings, critically assesses previous experimental data, and share perspectives on this important subject. |
Databáze: | OpenAIRE |
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