Glycosaminoglycans of the vertebral body growth plate in patients with idiopathic scoliosis

Autor:	A. M. Zaidman, T. V. Rusova, A. V. Korel, D. S. Tkachev, V. I. Rykova
Rok vydání:	2005
Předmět:	medicine.medical_specialty animal structures Adolescent Keratan sulfate Idiopathic scoliosis Scoliosis General Biochemistry Genetics and Molecular Biology Thoracic Vertebrae Glycosaminoglycan chemistry.chemical_compound Sulfation Internal medicine medicine Humans In patient Growth Plate Glycosaminoglycans Biological activity Acetylation General Medicine medicine.disease Spine carbohydrates (lipids) medicine.anatomical_structure Endocrinology chemistry Keratan Sulfate Case-Control Studies Thoracic vertebrae sense organs
Zdroj:	Bulletin of experimental biology and medicine. 139(6)
ISSN:	0007-4888
Popis:	The concentrations of keratan sulfates and unmodified keratan sulfates increased in the vertebral body growth plate in patients with idiopathic scoliosis. Sulfation and acetylation of total glycosaminoglycans decreased by 50 and 30%, respectively. These changes reflect the decrease in biological activity of molecules that modulate function of the growth plate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad9069d29ea9816be6ab24a79cb6254 https://pubmed.ncbi.nlm.nih.gov/16224597 Zobrazit plný text záznamu Full text from SpringerLink