Effectiveness of Puberty Suppression with Gonadotropin-Releasing Hormone Agonists in Transgender Youth

Autor: Ximena Lopez, Juan Diego Mejia-Otero, Perrin C. White
Rok vydání: 2021
Předmět:
Zdroj: Transgend Health
ISSN: 2380-193X
2688-4887
Popis: Purpose: To analyze the effectiveness of gonadotropin-releasing hormone agonists (GnRHa) in suppressing the hypothalamic-pituitary gonadal (HPG) axis in transgender adolescents. Methods: Retrospective review of electronic medical records of transgender youth and children with central precocious puberty (CPP) treated with GnRHa. Blood levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, and/or estradiol at baseline and during treatment were compared between groups. Results: Data from 30 transgender and 30 patients with CPP were analyzed. Transgender patients were older with a mean age of 13.0±2.1 years versus 7.7±2.3 years in the CPP group, p
Databáze: OpenAIRE