Characterization of Portal Vein Thrombus With the Use of Contrast-Enhanced Sonography
| Autor: | Hirokazu Takahashi, Satoru Saito, Masato Yoneda, Hiroyuki Kirikoshi, Takashi Sakaguchi, Norio Ueno, Shinji Togo, Harunobu Kawamura, Nobutaka Fujisawa |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Population Portal venous system Pulsatile flow Portal vein Contrast Media Malignancy Sensitivity and Specificity Diagnosis Differential Polysaccharides Risk Factors medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies cardiovascular diseases Thrombus education Prospective cohort study Aged Ultrasonography Aged 80 and over education.field_of_study Radiological and Ultrasound Technology Portal Vein business.industry Thrombosis Middle Aged medicine.disease Portal vein thrombosis cardiovascular system Female Radiology business circulatory and respiratory physiology |
| Zdroj: | Journal of Ultrasound in Medicine. 25:1147-1152 |
| ISSN: | 0278-4297 |
| DOI: | 10.7863/jum.2006.25.9.1147 |
| Popis: | Objectives To select an appropriate treatment regimen, it is essential to accurately characterize the nature of a thrombus. This study prospectively assessed the ability of contrast-enhanced sonography to differentiate between benign and malignant portal vein thrombosis in a population of high-risk patients. Methods Fifty-five patients (43 men and 12 women; mean age, 66 years; range, 55-83 years) with thrombi of the portal venous system were examined by power Doppler sonography and contrast-enhanced sonography with the intravenous contrast agent SH U 508A (Levovist; Schering AG, Berlin, Germany). Of the thrombi, 40 were characterized as malignant and 15 as benign. Pulsatile flow in the thrombus on power Doppler sonography and positive enhancement of the thrombus on contrast-enhanced sonography were judged as indications of a malignant thrombus. The sensitivity and specificity of both methods in differentiating the nature of the thrombus were evaluated. Results The detection of pulsatile flow in a portal vein thrombus as the criterion for diagnosing malignant portal vein thrombus yielded overall sensitivity of 82.5% and specificity of 100%, whereas positive enhancement of the portal vein thrombus itself as a criterion for diagnosing malignancy yielded overall sensitivity and specificity of 100% for each. Conclusions Contrast-enhanced sonography can be helpful in discriminating between benign and malignant portal vein thrombi. |
| Databáze: | OpenAIRE |
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