Incidental findings in whole-body MR imaging of a population-based cohort study: Frequency, management and psychosocial consequences
| Autor: | Holger Hetterich, Sigrid Auweter, Birgit Linkohr, Susanne Rospleszcz, Christopher L. Schlett, Annette Peters, Sabine Weckbach, Margit Heier, Fabian Bamberg, Birgit Ertl-Wagner, Sonja Selder, Roberto Lorbeer, Dorina Korbmacher |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty education.field_of_study Incidental Findings business.industry Whole body imaging Population General Medicine Mr imaging Magnetic Resonance Imaging Cohort Studies Germany Cohort Medicine Humans Radiology Nuclear Medicine and imaging Female Prospective Studies business education Prospective cohort study Psychosocial Depression (differential diagnoses) Cohort study |
| Zdroj: | European journal of radiology. 134 |
| ISSN: | 1872-7727 |
| Popis: | Objectives Management of incidental findings (IF) remains controversial but highly relevant. Our aim was to assess the frequency, management and psychosocial consequences of IF reporting in a population-based cohort study undergoing whole-body MR imaging. Methods The study was nested in a prospective cohort from a longitudinal, population-based cohort (KORA-FF4) in southern Germany. All MR obtained on 3 T MR scanner were reviewed by board-certified radiologists regarding clinically relevant IF. A baseline and follow-up questionnaires including PHQ-9 were completed prior to and 6-month after to the scan. Results Of 400 participants (56.3 ± 9.2years, 58 % male) undergoing whole-body MR, IF were found in 22 % of participants (n = 89); most frequently located in the abdominal sequences. In the pre-scan survey, most participants stated as the motivation that they wanted to “contribute to a scientific purpose” (91 %), while “knowing whether I’m healthy” was the most frequent motivation reported 6 months post-scan (88 %). The desire for IF reporting increased over time (pre- vs. 6-months-post-scan), also for clinically less important IF (72 % vs. 84 %, p = 0.001). Regarding psychosocial impact, a small portion (3.4 %) reported that awaiting the IF report added “definitely” or “very probably” additional stress burden. Of participants with reported IF, 56.8 % classified the results as “very helpful”. In the post-scan survey moderate depression was observed in 3.3 % and severe depression in 1.2 %. This did not differ between participants with and without reported IF. Conclusion In a cohort with whole-body MR imaging, the prevalence of IF was high. Participants considered reporting of IF highly important and added only minor psychological burden. |
| Databáze: | OpenAIRE |
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