Pharyngeal dilation in cricopharyngeus muscle dysfunction and Zenker diverticulum
| Autor: | Jacqueline Allen, Peter C. Belafsky, Rebecca J. Leonard, Catherine J. Rees |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Zenker Diverticulum
Male medicine.medical_specialty Contrast Media Constriction Contractility Cohort Studies chemistry.chemical_compound Internal medicine medicine Image Processing Computer-Assisted Humans Esophagus Aged Retrospective Studies business.industry Pharynx Retrospective cohort study Pharyngeal Diseases Middle Aged Esophageal Sphincter Upper Dysphagia Dilatation Surgery Barium sulfate medicine.anatomical_structure Otorhinolaryngology chemistry Fluoroscopy Cardiology Esophageal Stenosis Pharyngeal Muscles Female medicine.symptom Barium Sulfate business Deglutition Disorders Dilatation Pathologic |
| Zdroj: | The Laryngoscope. 120(5) |
| ISSN: | 1531-4995 |
| Popis: | Objectives/Hypothesis: Prolonged obstruction at the level of the lower esophageal sphincter is associated with a dilated, poorly contractile esophagus. The association between prolonged obstruction at the level of the upper esophageal sphincter (UES) and dilation and diminished contractility of the pharynx is uncertain. The purpose of this investigation was to evaluate the association between prolonged obstruction at the level of the UES and dilation and diminished contractility of the pharynx. Study Design: Case-control study. Methods: The fluoroscopic swallow studies of all persons with cricopharyngeus muscle dysfunction (CPD) diagnosed between January 1, 2006 and December 31, 2008 were retrospectively reviewed from a clinical database. Three categories of CPD were defined: nonobstructing cricopharyngeal bars (CPBs), obstructing CPBs, and Zenker diverticulum (ZD). The primary outcome measure was the pharyngeal constriction ratio (PCR), a surrogate measure of pharyngeal strength on fluoroscopy. Secondary outcome measures included pharyngeal area in the lateral fluoroscopic view and UES opening. The outcome measures were compared between groups and to a cohort of nondysphagic age- and gender-matched controls with the analysis of variance. Results: A total of 100 fluoroscopic swallow studies were evaluated. The mean age (±standard deviation) of the cohort was 70 years (±10 years). Thirty-six percent were female. The mean PCR progressively increased, indicating diminishing pharyngeal strength, from the normal (0.08), to the nonobstructing CPB (0.13), to the obstructing CPB (0.22), to the ZD group (0.28) (P < .001 with trend for linearity). There was a linear increase in pharyngeal area from the normal (8.75 cm2) to the nonobstructing CPB (10.00 cm2), to the obstructing CPB (10.46 cm2), to the ZD group (11.82 cm2) (P < .01 with trend for linearity). Conclusions: The data suggest that there is an association between cricopharyngeus muscle dysfunction and progressive dilation and weakness of the pharynx. Laryngoscope, 2010 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text