Improved cardiovascular risk profile of patients with type 1 diabetes mellitus and renal failure after simultaneous pancreas-kidney transplantation
| Autor: | A. Bravo Gutiérrez, J.M. González-Posada Delgado, L. Pérez Tamajón, A. Caballero Figueroa, I. Laynez Cerdeña, M. M. Meneses Fernández, D. Marrero Miranda, D. Hernández Marrero, A Hernández, L. Morcillo Herrera |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Lipoproteins Urology Renal function Body Mass Index Internal medicine Diabetes mellitus medicine Humans Diabetic Nephropathies Risk factor Triglycerides Glycated Hemoglobin Transplantation Type 1 diabetes business.industry nutritional and metabolic diseases medicine.disease Prognosis Endocrinology Blood pressure Diabetes Mellitus Type 1 Cardiovascular Diseases Kidney Failure Chronic Surgery Microalbuminuria Female business Risk Reduction Behavior Diabetic Angiopathies Kidney disease |
| Zdroj: | Transplantation proceedings. 37(9) |
| ISSN: | 0041-1345 |
| Popis: | Introduction. The prognosis of patients with type 1 diabetes mellitus and chronic renal failure improves after simultaneous pancreas-kidney (SPK) transplantation. Good control of glycemia and other cardiovascular risk factors may positively influence prognosis. The objective of this study was to evaluate changes in cardiovascular risk factors after SKP. Patients and methods. We studied 13 patients (aged 36 ± 8 years, 7 women) before and 12 months after SPK transplantation. All were treated with thymoglobulin, prednisone, tacrolimus, and mycophenolate mofetil. We compared the following pre- and post-SPK parameters: glycemia, HbA 1 c, total cholesterol, HDL, LDL, triglycerides, systolic (sBP), diastolic blood pressure (dBP), and body mass index (BMI). Results. Twelve months after SPK transplantation, glycemia, HbA 1 c and triglycerides significantly decreased (P |
| Databáze: | OpenAIRE |
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