Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients
| Autor: | Costa, Denise Maria do Nascimento, Coêlho, Maria Rosângela Cunha Duarte, Gouveia, Pedro Alves da Cruz, Bezerra, Luan Araújo, Marques, Claudia Diniz Lopes, Duarte, Angela Luzia Branco Pinto, Valente, Lucila Maria, Magalhães, Vera |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Igm antibody RC955-962 030106 microbiology 030231 tropical medicine Arthritis Case Report medicine.disease_cause Chikungunya fever Persistence (computer science) 03 medical and health sciences 0302 clinical medicine Arctic medicine. Tropical medicine parasitic diseases Medicine Chikungunya biology business.industry virus diseases medicine.disease Long term persistence Infectious Diseases Immunoglobulin M Immunology biology.protein Parasitology business |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 54 (2021) Revista da Sociedade Brasileira de Medicina Tropical |
| ISSN: | 1678-9849 0037-8682 |
| DOI: | 10.1590/0037-8682-0855-2020 |
| Popis: | The persistence of serum-specific anti-chikungunya IgM antibodies (CHIKV-IgM) can vary after chikungunya fever (CHIK) infection. However, the factors related to its production are not yet known. We described a case series drawn up from data collected from 57 patients between 12 and 36 months after the acute phase of CHIK infection in Northeastern Brazil. CHIKV-IgM was detectable in 7/57 (12.3%) patients after 28.3 months of infection. No frequency differences in chronic musculoskeletal manifestations and underlying conditions were detected between patients with or without CHIKV-IgM. CHIKV-IgM was detected for up to 35 months in Brazilian patients after CHIK infection. |
| Databáze: | OpenAIRE |
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