Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom National COVID-19 Surveillance Programmes

Autor: Anna Lo Jacomo, Mario Morvan, Vanessa Speight, Behnam Firoozi Nejad, Jasmine M. S. Grimsley, David L. Jones, Elena Armenise, Marcos Quintela-Baluja, Till Hoffmann, David W. Graham, Barbara Kasprzyk-Hordern, Kata Farkas, Cormac McSparron, Matthew J. Wade, Zhou Fang, Deidre F Gilpin, Chris J Lilley, Andrew C. Singer, John W. McGrath, Célia Souque, Alwyn Hart, Katherine J Jackson, Graeme J Cameron, Andrew J. Weightman, David I. Walker, Chris Sweetapple, Adrian M I Roberts, Joshua T. Bunce, Glenn Watts, Jennifer McKinley, Mathew R. Brown
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Health
Toxicology and Mutagenesis

Wastewater
Health Professions (miscellaneous)
Applied Microbiology and Biotechnology
Pandemic
Waste Management and Disposal
Uncertainty analysis
media_common
Public health
Uncertainty
Pollution
Agricultural and Biological Sciences (miscellaneous)
SDG 11 - Sustainable Cities and Communities
One Health
Work (electrical)
Health
Scale (social sciences)
Public Health
SDG 6 - Clean Water and Sanitation
Information Systems
Statistics and Probability
Wastewater-Based Epidemiological Monitoring
medicine.medical_specialty
Environmental Engineering
media_common.quotation_subject
Wastewater-based epidemiology
Environmental Science (miscellaneous)
Biochemistry
Genetics and Molecular Biology (miscellaneous)

Article
SDG 17 - Partnerships for the Goals
SDG 3 - Good Health and Well-being
medicine
Humans
Environmental Chemistry
Quality (business)
Pandemics
Environmental planning
Pace
Wastewater-based epidemiology Measurement variability
Uncertainty analysis
Public Health

SARS-CoV-2
COVID-19
Human pathogens
Business
Measurement variability
Zdroj: Wade, M, McKinley, J, McGrath, J, Gilpin, D, McSparron, C & Firoozi Nejad, B 2022, ' Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom National COVID-19 Surveillance Programmes ', Journal of Hazardous Materials, vol. 424, Part B, no. 127456 . https://doi.org/10.1016/j.jhazmat.2021.127456
Journal of Hazardous Materials
ISSN: 0304-3894
Popis: The COVID-19 pandemic has put unprecedented pressure on public health resources around the world. From adversity, opportunities have arisen to measure the state and dynamics of human disease at a scale not seen before. In the United Kingdom, the evidence that wastewater could be used to monitor the SARS-CoV-2 virus prompted the development of National wastewater surveillance programmes. The scale and pace of this work has proven to be unique in monitoring of virus dynamics at a national level, demonstrating the importance of wastewater-based epidemiology (WBE) for public health protection. Beyond COVID-19, it can provide additional value for monitoring and informing on a range of biological and chemical markers of human health. A discussion of measurement uncertainty associated with surveillance of wastewater, focusing on lessons-learned from the UK programmes monitoring COVID-19 is presented, showing that sources of uncertainty impacting measurement quality and interpretation of data for public health decision-making, are varied and complex. While some factors remain poorly understood, we present approaches taken by the UK programmes to manage and mitigate the more tractable sources of uncertainty. This work provides a platform to integrate uncertainty management into WBE activities as part of global One Health initiatives beyond the pandemic.
Graphical Abstract ga1
Databáze: OpenAIRE