The effect of smoking on corneal densitometry and endothelial cell morphology
Autor: | Fatma Corak Eroglu, Burcu Kazanci |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male Pathology medicine.medical_specialty Morphology (linguistics) Adolescent genetic structures Cell Count Toxicology medicine.disease_cause Corneal Diseases Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Photography medicine Humans Aged Aged 80 and over Smokers Chemistry Endothelium Corneal Smoking Corneal Topography Endothelial Cells Non-Smokers General Medicine Middle Aged eye diseases respiratory tract diseases Endothelial stem cell Cross-Sectional Studies SPECULAR MICROSCOPY behavior and behavior mechanisms 030221 ophthalmology & optometry Female sense organs Densitometry Oxidative stress |
Zdroj: | Cutaneous and Ocular Toxicology. 40:274-279 |
ISSN: | 1556-9535 1556-9527 |
Popis: | We investigated corneal endothelial morphology and corneal densitometry in smokers and compared our results with findings observed in non-smokers.This cross-sectional observational study included 100 participants (50 smokers, 50 non-smokers) aged 18-80 years in whom corneal endothelial morphology was analysed using a non-contact Tomey EM-4000 specular microscope (Tomey Corporation, Japan). The Pentacam HR system was used to measure corneal densitometry spatially in three concentric zones (from the centre to the periphery) and at three different corneal depths (from the anterior to the posterior aspects). Endothelial morphology findings and corneal densitometry values were recorded in all participants, and these results were compared between smokers and non-smokers.Endothelial morphology and corneal densitometry analysis showed significantly lower endothelial cell counts (Num) in smokers (228 cells/mmOur study highlights that among the morphometric corneal endothelial variables analysed in this study, only the Num value was significantly correlated with smoking. We observed no statistically significant intergroup difference in corneal densitometry values in this study; however, a positive correlation was observed between the number of pack-years and corneal densitometry findings. Therefore, as the pack-years increase, the increase in corneal densitometry values may indicate a decrease in corneal clarity, considering the possible contribution of secondary factors such as age. |
Databáze: | OpenAIRE |
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