Correlation between neonatal cranial ultrasound, MRI in infancy and neurodevelopmental outcome in infants with a large intraventricular haemorrhage with or without unilateral parenchymal involvement
| Autor: | I. C. van Haastert, L S de Vries, W P Vandertop, F. Groenendaal, K J Rademaker, L. C. Meiners, Rob H. J. M. Gooskens, P. Eken |
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| Přispěvatelé: | Neurosurgery, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, CCA - Cancer Treatment and quality of life, Other departments |
| Jazyk: | angličtina |
| Rok vydání: | 1998 |
| Předmět: |
Male
medicine.medical_specialty Developmental Disabilities Infant Premature Diseases Corpus callosum Severity of Illness Index Ventriculoperitoneal Shunt Cerebral palsy Central nervous system disease Lateral ventricles Child Development Medicine Humans Paralysis Prospective Studies Survivors Prospective cohort study Child Cerebral Hemorrhage medicine.diagnostic_test business.industry Vascular disease Cerebral Palsy Infant Newborn Brain Infant Magnetic resonance imaging General Medicine Cerebral Infarction medicine.disease Echoencephalography Magnetic Resonance Imaging Hyperintensity Surgery Child Preschool Pediatrics Perinatology and Child Health Brain Damage Chronic Female Neurology (clinical) business Wallerian Degeneration Infant Premature |
| Zdroj: | Neuropediatrics, 29(4), 180-8. Hippokrates Verlag GmbH Neuropediatrics, 29(4), 180-188. Hippokrates Verlag GmbH de Vries, L S, Rademaker, K J, Groenendaal, F, Eken, P, van Haastert, I C, Vandertop, W P, Gooskens, R & Meiners, L C 1998, ' Correlation between neonatal cranial ultrasound, MRI in infancy and neurodevelopmental outcome in infants with a large intraventricular haemorrhage with or without unilateral parenchymal involvement ', Neuropediatrics, vol. 29, no. 4, pp. 180-8 . https://doi.org/10.1055/s-2007-973558 |
| ISSN: | 0174-304X |
| DOI: | 10.1055/s-2007-973558 |
| Popis: | UNLABELLED: During a 7-year-period, 1625 infants of 34 weeks gestation or less were enrolled in a prospective ultrasound (US) study. One hundred and eleven (6.8%) infants developed a large intraventricular haemorrhage (IVH) with or without unilateral parenchymal involvement (PI). Fifty-six of these 111 infants survived (50.4%) and in 23 (41%) of them a magnetic resonance imaging (MRI) study was performed beyond 12 months corrected age. There appeared to be a good agreement between neonatal ultrasound findings and MRI changes noted in infancy. Of the 10 cases with a large IVH without PI (group A), seven had a VP shunt with complete decompression of previously enlarged ventricles. Six of these seven infants had periventricular hyperintensity (PVHI) but none developed cerebral palsy (CP). Two of the ten cases without a VP shunt had irregular ventricular enlargement (VE) with PVHI in one. Both developed CP. Seven cases showed thinning of the corpus callosum. Of the 13 cases with a large IVH associated with PI (group B), the site of the PI could still be recognised on MRI and the degree of communication of the porencephalic cyst (PC) with the lateral ventricles correlated well with neonatal US findings. On MRI, VE was present in only 6 cases. Wallerian degeneration was present in 9/13 infants and all but one developed a hemiplegia. In 12/13 cases there was thinning of the corpus callosum, either focal or diffuse. PVHI was present in all infants. In 6/13 PVHI was only present around the PC. Neurodevelopmental outcome differed for both groups. CP was only present in 2/10 infants in group A, compared to 11/ 13 in group B. Global delay, in the absence of CP, was more common in infants with a large IVH than in those with associated PI.CONCLUSION: Combining neonatal US with MRI in infancy enhances our understanding of the long-term effects of severe haemorrhagic brain lesions, occurring in preterm infants. |
| Databáze: | OpenAIRE |
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