Primary renal angiosarcoma: A case report and review of the literature
| Autor: | Nobuo Tsuda, Masachika Iseki, Masanobu Anami, Tomayoshi Hayashi, Paritosh Roy Chowdhury, Hiroshi Kanetake, Yoshio Horita, Yutaka Saito, Fukuzo Matsuya, Shigehiko Koga |
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| Rok vydání: | 1997 |
| Předmět: |
Male
Pathology medicine.medical_specialty Angiomyolipoma medicine.medical_treatment Hemangiosarcoma Antigens CD34 Pathology and Forensic Medicine Hemangioendothelioma Diagnosis Differential Fatal Outcome Humans Medicine Angiosarcoma Aged Kidney Ploidies business.industry Liver Neoplasms General Medicine medicine.disease Immunohistochemistry Kidney Neoplasms Nephrectomy Reticulin medicine.anatomical_structure Sarcoma Differential diagnosis Tomography X-Ray Computed business |
| Zdroj: | Pathology International. 47:778-783 |
| ISSN: | 1440-1827 1320-5463 |
| DOI: | 10.1111/j.1440-1827.1997.tb04457.x |
| Popis: | Primary renal angiosarcoma is very rare. To our knowledge, only 15 cases have been reported to date. A 77-year-old Japanese man with a unilateral kidney presented with massive hematuria followed by renal failure. A renal tumor was suspected and a left nephrectomy was performed. The histopathological diagnosis was angiosarcoma of the kidney. A hemorrhagic tumor measuring 10 x 5 cm and clotted blood was found in the medullary area. The atypical tumor cells had a sinusoidal and solid appearance, and showed immunohistochemically positive reactions for some of the endothelial markers. The patient died about 21 months after the nephrectomy and the autopsy revealed massive metastases to the liver and retroperitoneum. One of the differential diagnoses of the case was angiomyolipoma, because the tumor cells were relatively bland in their histological appearance with entrapped fat cells in the pelvic area. Fifteen case reports with titles that included the term 'hemangiosarcoma/angiosarcoma', 'hemangioendothelioma/endothelioma' or 'vascular sarcoma' of the kidney were reviewed and compared to the present case. |
| Databáze: | OpenAIRE |
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