Molecular and phenotypic characterization of methicillin-resistant Staphylococcus aureus isolates causing bacteremia at a major hospital in southern Mississippi

Autor: Stephanie N. Brown, Angela G. Crosby, Justin L. Batte, Luis A. Marcos, Dhritiman Samanta, Mohamed O. Elasri
Rok vydání: 2015
Předmět:
Methicillin-Resistant Staphylococcus aureus
Virulence Factors
Epidemiology
Bacterial Toxins
Exotoxins
Bacteremia
medicine.disease_cause
Article
Microbiology
Minimum inhibitory concentration
Mississippi
Antibiotic resistance
Leukocidins
Vancomycin
medicine
Humans
Molecular Epidemiology
Molecular epidemiology
business.industry
Health Policy
Public Health
Environmental and Occupational Health
Genetic Variation
Drug Tolerance
respiratory system
Staphylococcal Infections
biochemical phenomena
metabolism
and nutrition
bacterial infections and mycoses
medicine.disease
Methicillin-resistant Staphylococcus aureus
Hospitals
Anti-Bacterial Agents
Electrophoresis
Gel
Pulsed-Field
Infectious Diseases
Staphylococcus aureus
bacteria
Multilocus sequence typing
business
human activities
Multilocus Sequence Typing
medicine.drug
Zdroj: American Journal of Infection Control. 43:540-542
ISSN: 0196-6553
DOI: 10.1016/j.ajic.2015.01.023
Popis: Staphylococcus aureus is the predominant cause of bacteremia worldwide. We assessed the molecular epidemiology and antibiotic resistance of methicillin-resistant S aureus isolates causing bacteremia in southern Mississippi. Diverse genetic backgrounds in terms of staphylococcal cassette chromosome mec, pulsed-field gel electrophoresis, and multilocus sequence typing types of methicillin-resistant S aureus were identified as causing bacteremia in Mississippi. A strong association of Panton-Valentine leukocidin genes with elevated vancomycin minimum inhibitory concentration is one of the important findings of our study.
Databáze: OpenAIRE
Externí odkaz: