Adenoid Cystic Carcinoma of the Nasopharynx: A Case Report and a Discussion about Prognostic Factors and the Role of Local Treatments
| Autor: | Youssef, Elkholti, Alain, Cosmidis, Jean Michel, Ardiet, Lisa, Laffay, Berardino, De Bari |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Cancer Research Radiotherapy Planning Computer-Assisted Antineoplastic Agents Nasopharyngeal Neoplasms Chemoradiotherapy General Medicine Prognosis Carcinoma Adenoid Cystic Risk Assessment 030218 nuclear medicine & medical imaging stomatognathic diseases 03 medical and health sciences Treatment Outcome 0302 clinical medicine Oncology Chemotherapy Adjuvant Risk Factors 030220 oncology & carcinogenesis Humans Female Interdisciplinary Communication Radiotherapy Adjuvant Radiotherapy Intensity-Modulated Cisplatin |
| Zdroj: | Tumori Journal. 99:e55-e60 |
| ISSN: | 2038-2529 0300-8916 |
| Popis: | Adenoid cystic carcinoma (ACC) is a rare epithelioid malignancy. It occurs most frequently in the salivary glands, while its localization in the nasopharynx is rare and few cases have been reported in the literature. We report the case of a 32-year-old woman presenting with ACC of the nasopharynx who was treated with surgery and adjuvant intensity-modulated radiation therapy (IMRT, total dose: 68 Gy) and concomitant chemotherapy (cisplatin 100 mg/m2 on the first and 21st days of IMRT). During irradiation, the patient developed G1 dermatitis and G2 mucositis (RTOG). Clinical and instrumental reevaluation 17 months after the end of radiotherapy did not show any signs of relapse, and she did not show any sign of local mild-severe toxicity. Adjuvant radiotherapy after standard complete surgical resection seems to be effective and well tolerated and should be strongly considered in the multidisciplinary approach to this infrequent carcinoma. |
| Databáze: | OpenAIRE |
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