Evaluation of cerebral dysfunction in patients with chronic kidney disease using neuropsychometric and neurophysiological tests

Autor: Lilia Castillo-Martínez, Fabiola Sanchez-Meza, Luis E. Morales-Buenrostro, Aldo Torre, Sofía Sánchez-Román
Rok vydání: 2021
Předmět:
Adult
Male
medicine.medical_specialty
Adolescent
Psychometrics
030232 urology & nephrology
Flicker fusion threshold
Neuropsychological Tests
030204 cardiovascular system & hematology
Critical Care and Intensive Care Medicine
Severity of Illness Index
Gastroenterology
Flicker Fusion
Young Adult
03 medical and health sciences
Chronic kidney failure
uremia
0302 clinical medicine
Predictive Value of Tests
Internal medicine
Prevalence
medicine
Humans
In patient
Renal Insufficiency
Chronic
Cerebral dysfunction
uremic encephalopathy
cerebral dysfunction
business.industry
General Medicine
Middle Aged
chronic kidney failure
medicine.disease
Diseases of the genitourinary system. Urology
Uremia
body regions
Cross-Sectional Studies
Nephrology
Hepatic Encephalopathy
Clinical Study
Female
Uremic encephalopathy
RC870-923
business
Critical flicker frequency
Research Article
Kidney disease
Zdroj: Renal Failure
article-version (VoR) Version of Record
Renal Failure, Vol 43, Iss 1, Pp 577-584 (2021)
ISSN: 1525-6049
0886-022X
Popis: Background Uremic encephalopathy is defined as cerebral dysfunction due to toxin accumulation in patients with chronic kidney disease (CKD). This condition is characterized by subtle to florid symptoms, and its clinical course is always progressive when untreated but partially reversible with renal replacement therapy. While no test exists to measure subclinical uremic encephalopathy, two tests have been validated to measure minimal hepatic encephalopathy: the critical flicker frequency (CFF) test and the psychometric hepatic encephalopathy score (PHES). Objective To use CFF and PHES to measure the prevalence of cerebral dysfunction in individuals with CKD. Methods This cross-sectional study included a total of 69 patients with stage-5 CKD. Cutoff points for minimal encephalopathy were established using existing clinical guidelines: ≤39 Hz for CFF and
Databáze: OpenAIRE
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