Relationship between pernicious anaemia and gastric neuroendocrine cell disorders
| Autor: | A.M.E Spoelstra-de Man, C.B Brouwer, Sj.Sc. Wagenaar, A. Van Der Sluys Veer |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Gastritis
Atrophic Male medicine.medical_specialty Pathology Enterochromaffin-like Cells Anemia Atrophic gastritis Carcinoid Tumor Gastroenterology Pathogenesis Pernicious anaemia Stomach Neoplasms hemic and lymphatic diseases Internal medicine Anemia Pernicious Internal Medicine medicine Humans Neuroendocrine cell Aged Aged 80 and over business.industry Incidence (epidemiology) Hyperplasia medicine.disease digestive system diseases Pathophysiology medicine.anatomical_structure Gastric Mucosa business |
| Zdroj: | The Netherlands Journal of Medicine. 56:56-62 |
| ISSN: | 0300-2977 |
| DOI: | 10.1016/s0300-2977(99)00117-5 |
| Popis: | The incidence of gastric carcinoid tumours is increasing. This rise is probably due to the number of gastroscopies and improved histological techniques. The majority (65%) of these gastric tumours is associated with chronic atrophic gastritis and pernicious anaemia. In this article two patients are presented, one with pernicious anaemia and gastric neuroendocrine cell hyperplasia and one with pernicious anaemia and multiple gastric carcinoids. These neuroendocrine cell disorders have a relatively favourable prognosis. Therefore, a wait-and-see policy was preferred. The pathogenesis, clinical symptoms, diagnosis, prognosis and treatment of these different neuroendocrine cell manifestations are discussed. We recommend performing a gastroscopy at the time of diagnosis for young patients with pernicious anaemia, and whenever abdominal problems, unexplained weight loss or aggravation of the anaemia arise. |
| Databáze: | OpenAIRE |
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