Idiopathic Hyperlipemia and Primary Hypercholesteremic Xanthomatosis
| Autor: | Franz S. M. Herbst, Nancy A. Hurley, Walter F. Lever |
|---|---|
| Rok vydání: | 1955 |
| Předmět: |
Moving-boundary electrophoresis
medicine.medical_specialty biology Chemistry business.industry medicine.drug_class Anticoagulant Idiopathic hyperlipemia Paper electrophoresis Cell Biology Dermatology Heparin Blood proteins Biochemistry Protamine Electrophoresis Endocrinology Internal medicine medicine biology.protein business Molecular Biology medicine.drug |
| Zdroj: | Journal of Investigative Dermatology. 25:233-248 |
| ISSN: | 0022-202X |
| DOI: | 10.1038/jid.1955.126 |
| Popis: | In our study of patients with idiopathic hyperlipemia and primary hyper-cholesteremic xanthomatosis, the observation was made that heparin, on parenteral administration, because of its effect on the serum lipoproteins, produced characteristic changes in the electrophoretic and ultracentrifugal patterns of the serum in both diseases (1-4). Since protamine neutralizes the anticoagulant action of heparin (5) and is known to have an effect on the serum lipoproteins (6-9) it was decided to study the effects of protamine on the changes produced by heparin in the electrophoretic and ultracentrifugal patterns of patients with idiopathic hyperlipemia and primary hypercholesteremic xanthomatosis. |
| Databáze: | OpenAIRE |
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