Calf Form Bovine Leukosis with Lameness in a Holstein Heifer
| Autor: | Yuuki Nakanishi, Yoshiyasu Kobayashi, Hisashi Inokuma, Saori Miura, Mohammad Monir Tawfeeq, Kazuya Sugimoto, Hidefumi Furuoka |
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| Rok vydání: | 2012 |
| Předmět: |
Pathology
medicine.medical_specialty Lymphocytosis Lameness Animal Biopsy Fine-Needle Thymidine Kinase Peripheral blood mononuclear cell Fatal Outcome Synovial Fluid medicine Animals Synovial fluid Thymidine kinase 1 L-Lactate Dehydrogenase General Veterinary Reverse Transcriptase Polymerase Chain Reaction business.industry Histological Techniques Receptors Interleukin-2 Enzootic Bovine Leukosis Thymidine kinase Lameness Leukocytes Mononuclear Neoplastic cell Cattle Female Lymph Nodes medicine.symptom business Peripheral lymph |
| Zdroj: | Journal of Veterinary Medical Science. 74:1225-1228 |
| ISSN: | 1347-7439 0916-7250 |
| DOI: | 10.1292/jvms.12-0090 |
| Popis: | A 12-month-old Holstein heifer with anorexia, lameness, and enlargement of peripheral lymph nodes was suspected of having bovine leukosis. Although lymphocytosis was not observed, cytology of fine needle aspirate from a superficial cervical node, and increased serum lactate dehydrogenase and thymidine kinase activities, strongly suggested lymphosarcoma. Increased numbers of mononuclear cells as well as mitotic cells were observed in synovial fluid collected from swollen joints. Pathological examination confirmed B-cell calf form bovine leukosis and joint swelling related to neoplastic cell infiltration. Both interleukin-2 receptor and thymidine kinase 1 genes were highly expressed in cells from superficial cervical lymph node aspirate. |
| Databáze: | OpenAIRE |
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