Disulfiram Ethanol Reaction with Ischemic stroke
| Autor: | Sasidharan Sameer, C.S. Chandrashekhar Shetty, M Suresh Babu, M R Aiyappa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Tachycardia
Disulfiram ethanol reaction ischemic stroke business.industry Nausea Alcohol General Medicine Methemoglobinemia medicine.disease Disulfiram etanol reaksiyonu iskemik inme Bronchospasm chemistry.chemical_compound chemistry Anesthesia Shock (circulatory) Disulfiram Vomiting Medicine medicine.symptom business medicine.drug |
| Zdroj: | Volume: 11, Issue: 3 European Journal of General Medicine |
| ISSN: | 1304-3889 1304-3897 |
| Popis: | Disulfiram (tetraethylthiuram disulfide) has been used since decades in the treatment of alcohol addiction. It causes aversive behaviour towards alcohol due to Disulfiram Ethanol Reaction (DER). The classical DER includes flushing, sweating, tremors, nausea, vomiting, tachycardia, hypotension and restlessness. Complete recovery is the usual outcome in clinical settings. Life threatening reactions are rare but sometimes occur. Rare complications include shock, myocardial ischemia, hypertension, bronchospasm and methemoglobinemia. We present here a very rare case of ischemic stroke in a hemodynamically stable patient, which developed secondary to disulfiram–ethanol reaction. To the best of our knowledge, this is the first such reported case in literature. Disülfriram (tetraethylthiuram disulfide) on yıllardır alkol bağımlılığı tedavisinde kullanılmaktadır. Disülfiram Etanol Reaksiyonu (DER) nedeniyle alkole karşı caydırıcı davranışa neden olur. Klasik DER kızarma, terleme, tremor, bulantı, kusma, taşikardi, hipotansiyon ve huzursuzluk bulgularını içerir. Klinik merkezlerde tam iyileşme olağan sonuçtur. Hayatı tehdit edici reaksiyonlar nadirdir ancak bazen oluşabilir. Nadir reaksiyonlar; şok, miyokardiyal iskemi, hipertansiyon, bronkospazm ve methemoglobinemidir. Bu makalede DER’e sekonder olarak gelişen, hemodinamik olarak stabil bir hastada ortaya çıkan nadir bir iskemik inme vakasını sunduk. Bildiğimiz kadarıyla bu vaka literatürde bildirilen ilk vakadır |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|