Field-flow fractionation for nanoparticle characterization

Autor: Gaëtane Lespes, Valentin De Carsalade Du Pont
Přispěvatelé: Institut des sciences analytiques et de physico-chimie pour l'environnement et les materiaux (IPREM), Université de Pau et des Pays de l'Adour (UPPA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Rok vydání: 2021
Předmět:
Zdroj: Journal of Separation Science
Journal of Separation Science, Wiley-VCH Verlag, In press, ⟨10.1002/jssc.202100595⟩
ISSN: 1615-9314
1615-9306
DOI: 10.1002/jssc.202100595⟩
Popis: International audience; This review presents field-flow fractionation: The elements of theory enable the link between the retention and the characteristics of the nanometer-sized analytes to be highlighted. In particular, the nature of force and its way of being applied are discussed. Four types of forces which determine four types of techniques were considered: hydrodynamic, sedimentation, thermal, and electrical; this is to show the importance of the choice of technique in relation to the characterization objectives. Then the separation performance is presented and compared with other separation techniques: field-flow fractionation has the greatest intrinsic separation capability. The characterization strategies are presented and discussed; on the one hand with respect to the characteristics needed for the description of nanoparticles; on the other hand in connection with the choice of the nature of the force, and also of the detectors used, online or offline. The discussion is based on a selection of published study examples. Finally, current needs and challenges are addressed, and as response, trends and possible characterization solutions.
Databáze: OpenAIRE