Histopathological differences between genders in patients with oral squamous cell carcinoma
Autor: | Tássia Callai, Giulia Rubin Fuga, Fábio Muradás Girardi, Marina Fernandes Bianchi |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Oncology
medicine.medical_specialty lcsh:Medicine Disease carcinoma Gastroenterology Câncer Oral Tongue Internal medicine medicine Carcinoma In patient Oral Cavity Squamous Cell Carcinoma business.industry squamous cell Incidence (epidemiology) Oral neoplasms lcsh:R Cancer General Medicine Oral Neoplasm medicine.disease stomatognathic diseases medicine.anatomical_structure prognosis business |
Zdroj: | Clinical and Biomedical Research, Vol 37, Iss 3 (2017) Clinical & Biomedical Research; Vol. 37 No. 3 (2017) Clinical and Biomedical Research; v. 37 n. 3 (2017) Clinical and Biomedical Research Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
ISSN: | 2357-9730 0101-5575 |
Popis: | Introduction: Oral cancer ranks fifth among the most frequent malignant tumors in men in Brazil. The incidence of this tumor among women has grown. It is still controversial whether gender can influence the outcome or the prognostic features of the disease. Objectives : To compare the histopathological features of oral squamous cell carcinomas between genders among patients undergoing surgical treatment in an oncological hospital of southern Brazil. Methods: Between 2007 and 2011, 404 patients underwent resection of malignant tumors of the oral cavity in the head and neck department of this institution. A subgroup of 209 previously untreated oral cavity squamous cell carcinoma cases was selected for comparative analysis. Results: In total, 68 participants were women and 141 were men. The tongue was the most common subsite in both genders. Men presented lower mean age and women presented tumors with smaller depth of invasion. Although among women it was observed a trend towards tumors with less aggressive characteristics, no other variable showed statistically significance. Conclusion: Women with oral tumors tend to present more superficial primary tumors and at a later age. Keywords: Oral neoplasms; carcinoma; squamous cell; prognosis |
Databáze: | OpenAIRE |
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