The impact of axillary lymph node surgery on breast skin thickening during and after radiation therapy for breast cancer
| Autor: | Mylin A. Torres, Qi Long, Samantha Noreen, S. Henry, Hao Chen, Fundagal Andic, Donna Mister, Tatiana Han, Xiaofeng Yang, Tian Liu |
|---|---|
| Přispěvatelé: | Çukurova Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Cancer Research
medicine.medical_specialty Radiation business.industry medicine.medical_treatment Lumpectomy medicine.disease 030218 nuclear medicine & medical imaging Surgery Radiation therapy 03 medical and health sciences Dissection Axilla 0302 clinical medicine medicine.anatomical_structure Breast cancer Oncology 030220 oncology & carcinogenesis medicine Radiology Nuclear Medicine and imaging skin and connective tissue diseases business Prospective cohort study Lymph node Epidermal thickening |
| Popis: | PubMedID: 27055397 Purpose This prospective study was conducted to determine predictors of epidermal thickening during and after whole-breast radiation therapy (XRT) using objective measurements acquired with ultrasound. Methods and Materials After breast-conserving surgery, 70 women received a definitive course of whole-breast XRT (50 Gy plus boost). Prior to XRT, at week 6 of XRT, and 6 weeks after XRT, patients underwent objective ultrasound measurements of epidermal thickness over the lumpectomy cavity and all 4 quadrants of the treated breast. A skin thickness ratio (STRA) was then generated normalizing for corresponding measurements taken of the untreated breast. Results Baseline measurements indicated that 87% of patients had skin thickening in the treated versus untreated breast (mean increase, 27%; SD, 0.29) prior to XRT. The STRA increased significantly by week 6 of XRT (mean, 25%; SD, 0.46) and continued to increase significantly 6 weeks after XRT (mean, 33%; SD, 0.46) above baseline measurements (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|