Association between delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and joint space narrowing and osteophytes: a cohort study in patients with partial meniscectomy with 11 years of follow-up
| Autor: | Leif Dahlberg, Ewa M. Roos, Martin Englund, Henrik Owman, Carl Johan Tiderius, Jon Tjörnstrand, Ylva Ericsson |
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| Rok vydání: | 2013 |
| Předmět: |
Cartilage
Articular Male medicine.medical_specialty dGEMRIC Knee Joint Gadolinium Biomedical Engineering chemistry.chemical_element Osteoarthritis Menisci Tibial Cohort Studies Arthroscopy Rheumatology Risk Factors medicine Humans In patient Orthopedics and Sports Medicine Knee Glycosaminoglycans medicine.diagnostic_test business.industry Cartilage Osteophyte Magnetic resonance imaging DGEMRIC Middle Aged Osteoarthritis Knee medicine.disease Magnetic Resonance Imaging Surgery Radiography medicine.anatomical_structure chemistry Cohort Female business Nuclear medicine Cohort study Follow-Up Studies |
| Zdroj: | Owman, H, Ericsson, Y B, Englund, M, Tiderius, C J, Tjörnstrand, J, Roos, E M & Dahlberg, L E 2014, ' Association between delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and joint space narrowing and osteophytes : a cohort study in patients with partial meniscectomy with 11 years of follow-up ', Osteoarthritis and Cartilage, vol. 22, no. 10, pp. 1537–1541 . https://doi.org/10.1016/j.joca.2014.02.929 |
| ISSN: | 1522-9653 |
| Popis: | Objective: To examine the association between the relaxation time (T1Gd) of delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) and grade of tibiofemoral joint space narrowing (JSN) and osteophytosis 11 years later, in a cohort of meniscectomized patients. Design: Patients (. n=45) aged 35-50 who had undergone an arthroscopic partial medial meniscectomy 1-6 years earlier, due to degenerative meniscal tear, were examined using dGEMRIC. These patients had no cartilage changes defined as deep clefts or visible bone at the time of arthroscopy. Eleven years later (12-16 years after surgery) 34 of these subjects (76%) were evaluated by weight-bearing knee radiography, and tibiofemoral joint changes were graded according to the Osteoarthritis Research Society International Atlas. Results: Lower T1Gd in the medial compartment was associated with higher grade of medial JSN (grade 0, 351ms; grade 1, 386ms; grade 2, 342ms; grade 3, 259ms [. P for trend |
| Databáze: | OpenAIRE |
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