Constituintes químicos e atividade antiedematogênica de Peltodon radicans (Lamiaceae)
| Autor: | Habdel Nasser Rocha da Costa, Dorila Piló-Veloso, Maria Cristina dos Santos, Antônio F. C. Alcântara, Roberta Cabral França, Marilda Conceição da Silva |
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| Jazyk: | portugalština |
| Rok vydání: | 2008 |
| Předmět: | |
| Zdroj: | Química Nova, Volume: 31, Issue: 4, Pages: 744-750, Published: 2008 Química Nova v.31 n.4 2008 Química Nova Sociedade Brasileira de Química (SBQ) instacron:SBQ |
| Popis: | Most of the snakebite incidents in the Amazon region involve Bothrops atrox, whose venom presents the most potent edematogenic and necrotic activities in the genus. This work describes the studies of isolation of the chemical constituents and antiedematogenic activity of the species Peltodon radicans (Lamiaceae), which is used in the treatment of snakebites and scorpion stings in the region. The extracts presented aliphatic hydrocarbons, 3beta-OH,beta-amirin (1), 3beta-OH,alpha-amirin (2), beta-sitosterol (3), stigmasterol (4), ursolic acid (5), 2alpha,3beta,19alpha-trihydroxy-urs-12-en-28-oic acid (tormentic acid, 6), methyl 3beta-hydroxy,28-methyl-ursolate (7), sitosterol-3-O-beta-D-glucopyranoside (8), and stigmasterol-3-O-beta-D-glucopyranoside (9). The flower extracts presented the higher antiedematogenic activity. This is the first report on the study of the flowers, stem, and roots of this plant. |
| Databáze: | OpenAIRE |
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