Colonic sarcoidosis: Unusual onset of a systemic disease
| Autor: | Loredana Nugnes, Giovanni Vigliardi, Paola Erra, Anna Maria Pollio, Gianni Di Pilla, Sonia Crusco, Giuseppe Biondi |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Pathology medicine.medical_specialty Systemic disease Abdominal pain Constipation Sarcoidosis Biopsy medicine.medical_treatment Colonoscopy Case Report Malignancy Colonic Diseases Sarcoidosis Pulmonary Predictive Value of Tests Laparotomy medicine Humans Hemicolectomy Colectomy medicine.diagnostic_test business.industry Gastroenterology General Medicine Middle Aged medicine.disease Abdominal Pain Treatment Outcome medicine.symptom Tomography X-Ray Computed business Intestinal Obstruction |
| Zdroj: | World Journal of Gastroenterology. 21:3380-3387 |
| ISSN: | 1007-9327 |
| Popis: | Sarcoidosis is a multisystem chronic inflammatory condition of unknown etiology that has the potential to involve every tissue in the body. Sarcoidosis in the gastrointestinal system, and particularly the colon, is very rare. Here, we report the case of a 57-year-old man with no previous diagnosis of sarcoidosis who presented with new onset of abdominal pain and constipation. A colonoscopy revealed that the abdominal pain was caused by an obstructing lesion in the cecum-ascending colon and lacked a clear histologic diagnosis. Radiologic investigation revealed concentric wall thickening of the cecum-ascending colon with multiple satellite lymphadenopathies, highly suggestive of a malignancy. The patient underwent a laparotomy and a right hemicolectomy was performed. A diagnosis of colonic sarcoidosis was made after the resected specimen was examined. Additionally, a chest computed tomography scan revealed lung involvement with atypical radiologic features in the absence of respiratory symptoms. Only histologic examination of the surgical specimen can yield a diagnosis of gastrointestinal sarcoidosis due to the non-specificity of endoscopic and radiologic findings. |
| Databáze: | OpenAIRE |
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