Supplementary Figure 1 from miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma

Autor: Amy B. Heimberger, George A. Calin, Gregory N. Fuller, Ganesh Rao, Frederick F. Lang, Nicholas B. Levine, Wei Qiao, Olsi Gjyshi, Krishan Jethwa, Kayla McEnery, Yuhui Yang, Sherise D. Ferguson, Tiffany Doucette, Shuo Xu, Ling-Yuan Kong, Fei Wang, Jun Wei
Rok vydání: 2023
DOI: 10.1158/0008-5472.22394883
Popis: Supplementary Figure 1. PDF file 49K, (A) The relative expression of miR-124 as detected by TaqMan quantitative PCR in the CD11b+ GBM-infiltrating microglia/macrophages (n=4) is either very low or undetectable compared to normal brain tissues (n=3) (P < 0.01). (B) Summary dot plot demonstrating miR-124 expression is induced in gCSCs (n=8) upon neural differentiation (P < 0.01). Black filled circles: gCSCs; black filled squares: differentiated gCSCs. (C) Interleukin-8 (IL-8) (P < 0.05), galectin-3 (P < 0.01), and MIC-1 (P < 0.05) produced by gCSCs were reduced upon transfection with miR-124 compared with their levels in the scramble control
Databáze: OpenAIRE