Longitudinal study of breast cancer risk markers
| Autor: | Sheida Sharifi, Teresa Ann Gore, Abra H. Shen, Olivia Diamond, Musie Ghebremichael, Flora Rozhansky, Susan E. Pories, Prudence Lam, Corrine Zarwan, Margaret M. Lotz |
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| Rok vydání: | 2020 |
| Předmět: |
Oncology
medicine.medical_specialty Longitudinal study Lobular carcinoma Atypical lobular hyperplasia Breast Neoplasms Atypical hyperplasia 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine Internal Medicine medicine Humans Breast Longitudinal Studies skin and connective tissue diseases Hyperplasia business.industry Cancer medicine.disease Carcinoma Lobular Increased risk 030220 oncology & carcinogenesis Female Surgery Breast Carcinoma In Situ business Carcinoma in Situ |
| Zdroj: | The Breast Journal. 27:48-51 |
| ISSN: | 1524-4741 1075-122X |
| Popis: | Atypical hyperplasia (AH) and lobular carcinoma in situ (LCIS) are markers for an increased risk of breast cancer, yet outcomes for these diagnoses are not well-documented. In this study, all breast biopsies performed for radiologic abnormalities over a 10-year period were reviewed. Patients with AH or LCIS were followed for an additional 10 years to assess subsequent rates of cancer diagnosis. Long-term follow-up showed that 25 (7.8%) patients with AH and 5 patients with LCIS (5.7%) developed breast cancer over the follow-up period, a lower rate of breast cancer development than predicted by risk models. |
| Databáze: | OpenAIRE |
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