Virulence Characteristics and Phylogenetic Background of Ciprofloxacin Resistant Escherichia coli in the Urine Samples from Korean Women with Acute Uncomplicated Cystitis
| Autor: | Gilho Lee, Min Eui Kim, In Rae Cho, Yong Hyun Cho, Chul Sung Kim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Adolescent Genotype Urology Virulence Urine Microbial Sensitivity Tests Biology medicine.disease_cause Virulence factor Microbiology Young Adult Asian People Ciprofloxacin Virulence Factor Cystitis Drug Resistance Bacterial medicine Escherichia coli Humans Prospective Studies Prospective cohort study Escherichia coli Infections Phylogeny Aged General Medicine biochemical phenomena metabolism and nutrition Middle Aged Pyuria Bacterial Typing Techniques Original Article Female medicine.symptom medicine.drug |
| Zdroj: | Journal of Korean Medical Science |
| ISSN: | 1598-6357 1011-8934 |
| Popis: | To clarify the characteristics of the virulence factors (VFs) of ciprofloxacin resistant Escherichia coli (CFRE) with acute uncomplicated cystitis (AUC), we determined the VFs and the phylogenetic background of all 54 CFRE strains and the 55 randomly selected ciprofloxacin sensitive E. coli strains (CFSE) from patients with AUC in 22 Korean hospitals. The prevalence of the VFs was as follows: fimA, papEF, papGIII, sfaI, dafaBC, cnf1, and hlyA were presented in 96%, 54%, 68%, 91%, 49%, 72%, and 29% of the samples, respectively. The expressions of papEF, cnf1, and hlyA were significantly more prevalent in the CFSE. Moreover, the expressions of cnf, and papEF significantly reduced the risk of ciprofloxacin resistance. The CFSE was also marginally associated with the group B2 (P=0.05). Although the presence of pyuria and a previous cystitis history were not related with the phylotyping and the expressions of VFs, group B2, and fimA and papEF were more expressed in the younger age patients (P |
| Databáze: | OpenAIRE |
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