Leishmania donovani and Pneumocystis jirovecii (carinii) diagnosed on bronchoalveolar lavage cytology in a liver transplant recipient with Cytomegalovirus infection
| Autor: | Swapnil Dhampalwar, Abha Thakur, A.S. Soin, Sunita Kakkar, Haimanti Sarin, Sanjiv Saigal |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Histology medicine.medical_treatment Leishmania donovani Congenital cytomegalovirus infection 030209 endocrinology & metabolism Liver transplantation Pneumocystis carinii Chronic liver disease Bronchoalveolar Lavage Polymerase Chain Reaction Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Cytology Living Donors medicine Humans Pneumocystis jirovecii Lung medicine.diagnostic_test biology business.industry Pneumonia Pneumocystis General Medicine respiratory system biology.organism_classification medicine.disease Liver Transplantation respiratory tract diseases Bronchoalveolar lavage medicine.anatomical_structure 030220 oncology & carcinogenesis Cytomegalovirus Infections Immunology Leishmaniasis Visceral business Bronchoalveolar Lavage Fluid |
| Zdroj: | Diagnostic Cytopathology. 47:1194-1196 |
| ISSN: | 1097-0339 8755-1039 |
| Popis: | Liver transplant recipients are prone to several infections, including lung infections, which can lead to substantial morbidity and mortality. Bronchoalveolar lavage (BAL) cytology is a rapid and sensitive diagnostic tool to identify the etiologic agents. We report a rare case of a 24-year-old male, post Live donor liver transplantation for autoimmune chronic liver disease, who presented with cough, fever, weight loss, and cavitatory lesion in lung. BAL cytology revealed Leishmania donovani (LD) and Pneumocystis jirovecii/carinii (PCP). Cytomegalovirus deoxyribonucleic acid polymerase chain reaction (CMV DNA PCR) test showed markedly raised levels. Patient was put on treatment for these multiple infections and showed significant improvement. Thus, rapid diagnosis of infections through BAL cytology is crucial in transplant recipients to institute timely therapy and avoid undesirable empirical treatments. Moreover, this case highlights a rare finding of LD bodies along with PCP in BAL cytology. |
| Databáze: | OpenAIRE |
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