Renal function in prepubertal children born with very low birthweight
| Autor: | Sonia Hix, Simone Holzer, Denise de Oliveira Schoeps, Anelise Del Vecchio Gessulo, Fernando Luiz Affonso Fonseca, Roseli Oselka Saccardo Sarni, Fabíola Isabel Suano-Souza |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Male Endocrinology Diabetes and Metabolism Physiology Renal function Nutritional Status 030209 endocrinology & metabolism Overweight urologic and male genital diseases Kidney Excretion 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Medicine Humans Infant Very Low Birth Weight Child reproductive and urinary physiology Full Term Creatinine 030109 nutrition & dietetics Nutrition and Dietetics business.industry Blood pressure Cross-Sectional Studies chemistry Child Preschool Albuminuria Female medicine.symptom business Body mass index Glomerular Filtration Rate |
| Zdroj: | Nutrition (Burbank, Los Angeles County, Calif.). 62 |
| ISSN: | 1873-1244 |
| Popis: | Objectives The objective of this study was to evaluate estimated glomerular filtration rates (eGFR) and markers of renal function in very low birthweight (VLBW) children and to relate these parameters to current nutritional status. Methods A cross-sectional and controlled study was performed with prepubertal children between ages 5 and 10, including 44 VLBW participants and 30 healthy participants born at full term with an adequate birthweight (control group). The following data were collected: perinatal history; current weight, height and waist circumference; blood pressure (three measures); blood creatinine, urea, uric acid, cystatin-C, and neutrophil gelatinase-associated lipocalin levels; and urine albumin, creatinine, and calcium levels. Results Blood pressure, eGFR, albuminuria, concentrations of cystatin-C, neutrophil gelatinase-associated lipocalin, uric acid, urea, creatinine, and fractional calcium excretion did not differ between VLBW and control groups. Regarding the VLBW group, there was no difference in eGFR, albuminuria, and other markers of renal injury in overweight or obese children compared with children with a normal body mass index. Conclusions Prepubertal children born with VLBW did not have altered renal function, regardless of their current nutritional status. |
| Databáze: | OpenAIRE |
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