Safety of Human Embryonic Stem Cell-derived Mesenchymal Stem Cells for Treating Interstitial Cystitis: A Phase I Study
Autor: | Jung Hyun Shin, Chae-Min Ryu, Hwan Yeul Yu, Juhyun Park, Ah Reum Kang, Jeong Min Shin, Ki-Sung Hong, Eun Young Kim, Hyung-Min Chung, Dong-Myung Shin, Myung-Soo Choo |
---|---|
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Stem Cells Translational Medicine. 11:1010-1020 |
ISSN: | 2157-6580 2157-6564 |
Popis: | There are still no definite treatment modalities for interstitial cystitis (IC). Meanwhile, stem cell therapy is rising as potential alternative for various chronic diseases. This study aimed to investigate the safety of the clinical-grade mesenchymal stem cells (MSCs) derived from human embryonic stem cells (hESCs), code name MR-MC-01 (SNU42-MMSCs), in IC patients. Three female IC patients with (1) symptom duration >6 months, (2) visual pain analog scale (VAS) ≥4, and (3) one or two Hunner lesions |
Databáze: | OpenAIRE |
Externí odkaz: |