Papillomaviruses: a systematic review
Autor: | Márcio Augusto Caldas Rocha de Carvalho, Suely Muro Reis Assaf, Willy Beçak, Jacqueline de Souza, Roberta Fiusa Magnelli, Diego Grando Módolo, R.F. Carvalho, Rodrigo Pinheiro Araldi, R.C. Stocco, Franco Roperto |
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Přispěvatelé: | Araldi, Rp, Assaf, Sm, Carvalho, Rf, Carvalho, Ma, Souza, Jm, Magnelli, Rf, Módolo, Dg, Roperto, FRANCO PEPPINO, Stocco, Rc, Beçak, W. |
Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Cervical cancer lcsh:QH426-470 bovine papillomatosis Experimental model viruses Cancer Biology medicine.disease Bioinformatics Virology bovine papillomavirus (BPV) lcsh:Genetics 03 medical and health sciences 030104 developmental biology Special Series of Articles - 60 Years of The Brazilian Society of Genetics natural history Genetics medicine Cancer development Molecular Biology carcinogenesis |
Zdroj: | Genetics and Molecular Biology v.40 n.1 2017 Materials research (São Carlos. Online) Universidade Federal de São Carlos (UFSCAR) instacron:ABM ABC ABPOL Genetics and Molecular Biology Genetics and Molecular Biology, Iss 0 Genetics and Molecular Biology, Volume: 40, Issue: 1, Pages: 1-21, Published: 16 FEB 2017 |
Popis: | In the last decades, a group of viruses has received great attention due to its relationship with cancer development and its wide distribution throughout the vertebrates: the papillomaviruses. In this article, we aim to review some of the most relevant reports concerning the use of bovines as an experimental model for studies related to papillomaviruses. Moreover, the obtained data contributes to the development of strategies against the clinical consequences of bovine papillomaviruses (BPV) that have led to drastic hazards to the herds. To overcome the problem, the vaccines that we have been developing involve recombinant DNA technology, aiming at prophylactic and therapeutic procedures. It is important to point out that these strategies can be used as models for innovative procedures against HPV, as this virus is the main causal agent of cervical cancer, the second most fatal cancer in women. |
Databáze: | OpenAIRE |
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