Incidence of subclinical atrial fibrillation in a South Asian population

Autor:	Muzahir H. Tayebjee, Lina Jegodzinski, James O’Neill
Rok vydání:	2018
Předmět:	Male medicine.medical_specialty Pacemaker Artificial medicine.medical_treatment South asian population Cardiac resynchronization therapy 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal medicine Atrial Fibrillation Medicine Humans Cumulative incidence 030212 general & internal medicine Stroke Asia Southeastern Subclinical infection Aged Retrospective Studies business.industry Incidence (epidemiology) Incidence Atrial fibrillation Retrospective cohort study General Medicine medicine.disease England Female Cardiology and Cardiovascular Medicine business
Zdroj:	Pacing and clinical electrophysiology : PACE. 41(12)
ISSN:	1540-8159
Popis:	BACKGROUND South Asians have a lower prevalence of atrial fibrillation (AF) compared with Caucasians despite higher rates of conventional risk factors and a higher incidence of stroke. It is not clear whether South Asians truly experience less AF or whether this is due to underdetection of the arrhythmia. Therefore, we aimed to determine whether South Asian patients with pacemakers have a lower incidence of device-detected subclinical episodes of AF compared with Caucasian controls. METHODS We performed a retrospective cohort study of South Asian and Caucasian patients who underwent pacemaker implantation between 2006 and 2016. Subclinical AF episodes, detected during subsequent device clinic follow-up visits, were identified and the occurrence of clinical AF, cerebrovascular events, and all-cause mortality was recorded. RESULTS A total of 5 648 patients underwent pacemaker implantation at the Yorkshire Heart Centre, UK, during the study period. Of these, 169 were South Asian and 72 met the eligibility criteria. The cumulative incidence of subclinical AF was significantly lower in South Asians compared with Caucasians (logrank P = 0.002) with an annual event rate of 6.9% versus 13.9%, and South Asian ethnicity was an independent predictor of a lower incidence of subclinical AF (odds ratio = 0.43; 95% confidence interval = 1.01-5.38). CONCLUSIONS South Asians with an implanted pacemaker have a lower rate of subclinical AF compared with Caucasians.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a47befec50fdc1504f0bf12629ef93f https://pubmed.ncbi.nlm.nih.gov/30839111 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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