Uterine leiomyosarcoma with osteoclast like giant cells and long standing systemic symptoms
| Autor: | György Illyés, Lajos Kosa, Zoltan Vajo, Kálmán Patai, János Gidai, Szabolcs Várbíró |
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| Rok vydání: | 2006 |
| Předmět: |
Leiomyosarcoma
Pathology medicine.medical_specialty medicine.medical_treatment Uterus Osteoclasts Inflammation Giant Cells Osteoclast medicine Humans Hysterectomy Uterine sarcoma business.industry Obstetrics and Gynecology Middle Aged medicine.disease medicine.anatomical_structure Oncology Giant cell Uterine Neoplasms Immunohistochemistry Female medicine.symptom business |
| Zdroj: | Gynecologic oncology. 102(2) |
| ISSN: | 0090-8258 |
| Popis: | Introduction. The leiomyomatous type of uterine sarcoma with osteoclast-type giant cell component is a rare variant of uterine tumors with poor prognosis. The histological diagnosis of these rare tumors can be problematic and only five such tumors have been published previously. Case Report. A 54-year-old woman presented with fever and weight loss for 7 months and laboratory findings suggestive of inflammation. After extensive clinical investigation, a uterine tumor was found, which was considered to be an incidental finding and was thought to be unlikely to explain the symptoms. After hysterectomy, the patient had a surprising and quick recovery with the complete relief of systemic symptoms and normalization of laboratory changes. The tumor was a dedifferentiated leiomyosarcoma with osteoclast-like giant cells and contained extensive necrosis. The patient continues to do well and is tumor-free 1 year after the operation. Discussion. To our knowledge, this is the first report of a patient being alive and disease-free 12 months after surgery with a dedifferentiated uterine leiomyosarcoma with osteoclast-like giant cells. |
| Databáze: | OpenAIRE |
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