Spontaneous reconstitution of the mammalian intestinal tract following complete transection

Autor: Allan E. Dumont, Amalia B. Martelli, Henny Iliescu, Michael Baron
Rok vydání: 1980
Předmět:
Zdroj: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 164(4)
ISSN: 0037-9727
Popis: To determine whether the mammalian intestinal tract is capable of reconstituting itself following complete transection, a 1-cm segment of the small or large bowel was excised in 44 rats. In an additional group of 52 rats the colon was transected distal to a diverting colostomy. In each case the open-cut ends of the intestine were simply dropped back into the peritoneal cavity and the abdominal incision was closed with sutures. Eight animals survived simple transection (18%) regaining functional intestinal continuity in 2 weeks and a morphologically normal appearing intestine in 1 month. When the colon was transected distal to a diverting colostomy the survival rate increased almost four-fold with complete reconstitution of the transected segment in 80% of the survivors.
Databáze: OpenAIRE