Insights on the Molecular Characteristics of Molecularly Imprinted Polymers as Monitored by Sum Frequency Generation Spectroscopy
| Autor: | Imee Su Martinez, Paul Cudia, Romelyn Obiles, Uriel Joseph Erasquin, Katherine Cimatu, Uvinduni I. Premadasa, Jenna M. Berger |
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| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
Molecularly imprinted polymer 02 engineering and technology Surfaces and Interfaces Polymer 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences chemistry Chemical engineering Electrochemistry Molecule General Materials Science 0210 nano-technology Spectroscopy Sum frequency generation spectroscopy |
| Zdroj: | Langmuir. 36:180-193 |
| ISSN: | 1520-5827 0743-7463 |
| DOI: | 10.1021/acs.langmuir.9b02927 |
| Popis: | Sensing in molecularly imprinted polymers (MIPs) requires specific interactions of the imprinted polymer and the approaching template molecule. These interactions are affected by the morphology of the polymer surface, the affinity of the template molecule to the polymer network, and the steric approach. In this particular study, a template molecule, metronidazole, is studied with respect to the typically used methacrylic acid-based imprinted polymer using a combination of bulk and surface techniques. The resulting infrared (IR) spectra exhibited the presence of the template molecule in the polymer matrix as well as their efficient removal after washing. Dipping of the MIP according to what is expected of facile sensing in an aqueous solution of metronidazole did not show any presence of the template molecule in the bulk of the MIP, as observed by IR spectroscopy. However, using sum frequency generation (SFG) spectroscopy, the CH aromatic stretch of the imidazole ring positioned at ∼3100 cm |
| Databáze: | OpenAIRE |
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