Network meta‐analysis of His bundle, biventricular, or right ventricular pacing as a primary strategy for advanced atrioventricular conduction disease with normal or mildly reduced ejection fraction
| Autor: | Amanda Fernandes, Manuel Rivera, Litsa K. Lambrakos, Leonardo Knijnik, Raul D. Mitrani, Gilson Fernandes, Juan Lopez, Jeffrey J. Goldberger, Robert J. Myerburg |
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| Rok vydání: | 2020 |
| Předmět: |
Bundle of His
medicine.medical_specialty Time Factors medicine.medical_treatment Network Meta-Analysis Cardiac resynchronization therapy Action Potentials Disease 030204 cardiovascular system & hematology Risk Assessment Ventricular Function Left Cardiac Resynchronization Therapy 03 medical and health sciences QRS complex 0302 clinical medicine Heart Rate Risk Factors Physiology (medical) Internal medicine medicine Humans 030212 general & internal medicine Atrioventricular Block business.industry Cardiac Pacing Artificial Stroke Volume Odds ratio Ventricular pacing medicine.disease Treatment Outcome Heart failure Meta-analysis Ventricular Function Right Cardiology Mildly reduced ejection fraction Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Cardiovascular Electrophysiology. 31:1482-1492 |
| ISSN: | 1540-8167 1045-3873 |
| DOI: | 10.1111/jce.14490 |
| Popis: | INTRODUCTION Although right ventricular pacing (RVP) may impair ventricular function, it is commonly used for advanced atrioventricular block (AVB) and normal or mildly reduced ejection fraction (EF). We aimed to compare His bundle pacing (HBP), biventricular pacing (BiVP), and RVP for advanced AVB in patients with normal or mildly reduced EF. METHODS AND RESULTS MEDLINE, Embase, Cochrane CENTRAL, ClinicalTrials.gov, Scopus, and Web of Science were searched. Outcomes were all-cause death, heart failure hospitalizations (HFH), EF, left ventricular volumes, 6-minute walk test, and QRS duration. HBP or BiVP was compared with RVP. Subsequently, network meta-analysis compared the three pacing options. Our protocol was registered in PROSPERO (CRD42018094132). Six studies compared BiVP and RVP (704 vs 614 patients) and four compared HBP and RVP (463 vs 568 patients). Follow-up was 6 months to 5 years. There was significantly lower mortality and HFH with HBP or BiVP as compared with RVP (odds ratio [OR], 0.66, [0.51-0.85], P = .002; OR, 0.61 [0.45-0.82], P |
| Databáze: | OpenAIRE |
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