Interactions of oxidant stress and vascular reactivity
| Autor: | G. H. Gurtner, T. Burke-Wolin |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Pulmonary and Respiratory Medicine
Pulmonary Circulation medicine.medical_specialty Physiology Vasodilation Pulmonary Artery chemistry.chemical_compound tert-Butylhydroperoxide Physiology (medical) Internal medicine medicine Animals Oxygen toxicity Vasomotor fungi food and beverages Cell Biology Smooth muscle contraction medicine.disease Peroxides Oxygen Endocrinology medicine.anatomical_structure chemistry Vasoconstriction Circulatory system Biophysics Arachidonic acid Signal transduction Blood vessel |
| Zdroj: | American Journal of Physiology-Lung Cellular and Molecular Physiology. 260:L207-L211 |
| ISSN: | 1522-1504 1040-0605 |
| DOI: | 10.1152/ajplung.1991.260.4.l207 |
| Popis: | Oxidants have complex effects on pulmonary vascular reactivity. They can stimulate production of vasoconstrictor arachidonate mediators and can also cause vasodilation through activation of guanylate cyclase. Oxidants can also inactivate vasomotor phenomenon by interfering with mechanisms of signal transduction or smooth muscle contraction. The final physiological response depends on the balance of these complex actions. |
| Databáze: | OpenAIRE |
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