Imaging fluorophore-labelled intestinal tissue via fluorescence endoscope capsule
| Autor: | James Beeley, David R. S. Cumming, Sandy Cochran, Fraser Stewart, Mohammed Al-Rawahani, Gianluca Melino, Mihnea V. Turcanu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Fluorescence-lifetime imaging microscopy
Fluorophore Endoscope tissue fluorescence capsule endoscopy Capsule lcsh:A Fluorescence Small intestine law.invention chemistry.chemical_compound medicine.anatomical_structure fluorescence labelling chemistry fluorescence imaging Capsule endoscopy law medicine lcsh:General Works Ex vivo Biomedical engineering |
| Zdroj: | Proceedings, Vol 2, Iss 13, p 766 (2018) |
| ISSN: | 2504-3900 |
| Popis: | The authors have developed a wireless fluorescence imaging capsule endoscope, potentially capable of detecting early signs of disease in the human intestine which can be missed by white-light imaging (WLI) capsule endoscopy (Figure 1). Intestinal fluorescence imaging exploits variations in tissue autofluorescence between healthy and diseased areas in response to illumination, or application of fluorescent labels which preferentially bind to diseased sites. To validate the capsule’s capability to image fluorescently-labelled tissue, a small area of a sample of ex vivo porcine small intestine was sonicated with 6 nm CdZnMg fluorescent quantum dots, and the labelled area clearly differentiated from surrounding tissue by the fluorescence imaging capsule. |
| Databáze: | OpenAIRE |
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