The effectiveness of the Milan system for risk stratification of salivary gland lesions: The 10-year cytohistopathological correlation results of salivary gland FNA cytology at a tertiary center
| Autor: | Merve Meryem Kiran, Aysegul Aksoy Altinboga, Fatma Yildirim, Hilal Ahsen, Gulin Gokcen Kesici, Gokhan Yuce |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Histology Adolescent Cytodiagnosis Biopsy Fine-Needle 030209 endocrinology & metabolism Malignancy Risk Assessment Salivary Glands Pathology and Forensic Medicine 03 medical and health sciences Young Adult 0302 clinical medicine Cytology Atypia Medicine Humans Child Aged Retrospective Studies Aged 80 and over Suspicious for Malignancy Salivary gland business.industry General Medicine Middle Aged medicine.disease Salivary Gland Neoplasms medicine.anatomical_structure Cytopathology 030220 oncology & carcinogenesis Histopathology Female Salivary gland neoplasm Radiology business |
| Zdroj: | Diagnostic cytopathologyREFERENCES. 49(8) |
| ISSN: | 1097-0339 |
| Popis: | BACKGROUND The Milan system reporting salivary gland cytopathology (MSRSGC) is a tiered classification scheme that is based on risk stratification. The aim of the current study was to assess the risk of malignancy (ROM) and risk of neoplasia (RON) in each of the diagnostic categories proposed by the MSRSGC. METHODS A retrospective analysis and categorization according to the MSRSGC was made of salivary gland fine needle aspirations (FNA) performed from January 2007 to December 2017. The FNA cytology results were correlated with subsequent histological follow-up. RESULTS A total of 578 FNAs were evaluated and histopathology was available for 198 cases (34.2%). The RON and ROM for individual diagnostic categories were: Non-diagnostic: 52.2% to 13%, non-neoplastic: 21.4% to 10.7%, atypia of undetermined significance: 74% to 22.2%, benign neoplasm: 100% to 1.1%, salivary gland neoplasm of uncertain malignant potential: 93.3% to 53.3%, suspicious for malignancy (SFM): 100% to 100%, and malignant: 100% to 100%. A diagnosis of 'SFM' or 'malignant' with FNA cytology carried a 100% risk for malignancy, while a diagnosis of "non-neoplastic," "benign neoplasm" reduced the probability of malignancy to 3.4%. CONCLUSION The MSRSGC is useful for the management of salivary gland lesions as it can successfully differentiate between benign and malignant cases. It will bring uniformity in salivary gland FNA cytology reporting across various institutions globally. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text