Intralesional administration of interferon A for the management of severe haemangiomas
| Autor: | G Papouis, V Kaselas, C Kaselas, G Tsikopoulos |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Skin Neoplasms Alpha interferon Angiogenesis Inhibitors Soft Tissue Neoplasms Injections Intralesional Malaise Hemangioma Interferon Pediatric surgery medicine Humans Major complication business.industry Infant Interferon-alpha General Medicine medicine.disease Surgery Prior Therapy Child Preschool Radiological weapon Pediatrics Perinatology and Child Health Female medicine.symptom business medicine.drug |
| Zdroj: | Pediatric Surgery International. 23:215-218 |
| ISSN: | 1437-9813 0179-0358 |
| DOI: | 10.1007/s00383-006-1840-3 |
| Popis: | Intralesional administration of interferon alpha (INF-A) is a new approach in haemangiomas treatment that we electively apply to our patients. The aim of this study is to report the beneficial results of this new kind of therapy. Thirty-two patients with severe haemangiomas, 19 females and 13 males, were treated at our department from January 2000 to December 2004. All patients received INF-A intralesionally at a dose of 1-3 MIU/m(2) of body surface once a day for the first week, and then once a week until completion of therapy. Reduction was evaluated after clinical and radiological measurement before, during and after completion of therapy and was graded as complete (>80%), significant (50-80%), medial (20-50%) and no response ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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