Influence of emotional-algic stress on the activity of carboxypeptidase H — An enzyme involved in processing rat brain neuropeptides
Autor: | A. N. Vernigora, Gengin Mt |
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Rok vydání: | 1995 |
Předmět: |
Male
medicine.medical_specialty Emotions Hypothalamus Pain Neuropeptide Peptide Carboxypeptidases Biology Pituitary Gland Posterior Internal medicine medicine Animals Brain Chemistry chemistry.chemical_classification General Neuroscience Neuropeptides Brain Carboxypeptidase H Rat brain Carboxypeptidase Electric Stimulation Rats Enzyme Endocrinology Acoustic Stimulation chemistry Biochemistry biology.protein Stress Psychological |
Zdroj: | Neuroscience and Behavioral Physiology. 25:307-310 |
ISSN: | 1573-899X 0097-0549 |
DOI: | 10.1007/bf02360042 |
Popis: | It was established that the activity of carboxypeptidase H increases in divisions of the brain of rats during a one-time emotional-algic stress. The most substantial increase in the activity of the enzyme is observed in the hypophysis and the hypothalamus. The changes in activity were less marked with chronic emotional-algic stress. The involvement of carboxypeptidase H in the development of stress reactions, as well as the possibility of the participation of the soluble form of the enzyme in the processing of secretory peptides, and of the membrane-bound form in the processing, of neuropeptides with a central action, is hypothesized. |
Databáze: | OpenAIRE |
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