CLOSTRIDIUM PERFRINGENS BACTERIOPHAGE EFFECT ON MACROPHAGES FUNCTIONAL ACTIVITY
| Autor: | Т. Бaрбутaшвiлi |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Chemistry
lcsh:Biotechnology Spleen Clostridium perfringens medicine.disease_cause In vitro Microbiology Peritoneal cavity фактор некрозу пухлин а medicine.anatomical_structure In vivo lcsh:TP248.13-248.65 medicine Macrophage Tumor necrosis factor alpha бактерiофаг clostridium perfringens функціональна активність макрофагiв Incubation |
| Zdroj: | Mìkrobìologìâ ì Bìotehnologìâ, Vol 0, Iss 1(2), Pp 23-28 (2008) |
| ISSN: | 2307-4663 2076-0558 |
| DOI: | 10.18524/2307-4663.2008.1(2).103720 |
| Popis: | We have shown that Clostridium perfringens bacteriophage both in vivo and in vitro supresses the phagocytic activity of peritoneal cavity and spleen macrophages as well as restoration of nitro blue tetrazollium. The effect depends on duration of treatment and preparation concentration in incubation media. All changes in cell activity are entailed with the increase of tumor necrosis factor а synthesis in organism as well as in macrophage culture in vitro. The preparation does not have any direct toxic effect on macrophages. |
| Databáze: | OpenAIRE |
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