Resistance to BN myelogenous leukemia in rat radiation chimeras
| Autor: | D R Haynor, D E Singer, R M Williams |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Cancer Research
Graft vs Host Reaction Biology Major Histocompatibility Complex Myelogenous Chimera (genetics) Antigen Rats Inbred BN medicine Animals Transplantation Homologous Bone Marrow Transplantation Neoplasms Experimental Hematology medicine.disease Molecular biology Rats Transplantation Leukemia Graft-versus-host disease medicine.anatomical_structure Oncology Leukemia Myeloid Rats Inbred Lew Radiation Chimera Immunology Bone marrow |
| Zdroj: | Leukemia Research. 4:337-342 |
| ISSN: | 0145-2126 |
| DOI: | 10.1016/0145-2126(80)90088-0 |
| Popis: | Lewis → LBNF1 rat radiation chimeras showed marked resistance to transplanted BN myelogenous leukemia when compared to naive LBNF1, LBNF1 → LBNF1, or BN → LBNF1. This occurred in the absence of overt graft versus host disease or of anti-BN response in mixed lymphocyte culture. Bone marrow specific antigens may serve as the target of the resistance mechanism. |
| Databáze: | OpenAIRE |
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