Ecdysis triggering hormone peptide in the African malaria mosquito Anopheles gambiae: The peptide structure for receptor activation

Autor: Hawa Dembele, Moritz Mating, Rupinder Singh, Soheila Fatehi, Alvaro I. Herrera, Yoonseong Park, Om Prakash
Rok vydání: 2021
Předmět:
Zdroj: Insect science. 29(5)
ISSN: 1744-7917
Popis: Infections by mosquito-borne diseases represent one of the leading causes of death in third world countries. The rapid progression of resistance to conventional insecticide causes a significant threat to the highly efficient preventive methods currently in place. Insect neuropeptidergic system offers potential targets to control the insect vectors. The essential roles of the neuropeptide ecdysis triggering hormone (ETH) in insect development and reproduction led us to attempt understanding of the fundamentals of the biochemical interaction between ETH and its receptor in the African malaria mosquito Anopheles gambiae. One of two ETH peptides of the African malaria mosquito (AgETH1), a small peptide hormone with 17 amino acid residues (SESPGFFIKLSKSVPRI-NH
Databáze: OpenAIRE