Crystalline Lens Optical Dysfunction through Aging
| Autor: | Jorge L. Alió, Robert Montés-Micó, Herminio P. Negri, Patricia Schimchak |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Visual acuity Adolescent genetic structures Visual Acuity law.invention Lens thickness law Optical transfer function Ophthalmology Lens Crystalline Photography medicine Humans Child Aged Aged 80 and over business.industry Anatomy Middle Aged eye diseases Optical quality Lens (optics) Spherical aberration Cross-Sectional Studies Ageing Female sense organs medicine.symptom Densitometry business |
| Zdroj: | Ophthalmology. 112:2022-2029 |
| ISSN: | 0161-6420 |
| DOI: | 10.1016/j.ophtha.2005.04.034 |
| Popis: | To evaluate the optical and densitometric changes that take place in the crystalline lens with aging.Cross-sectional study.Seventy-two eyes of 72 patients of different ages (8-80 years) with a clear lens, a visual acuity of 20/25 or better, and no ocular disease.In each case, the lens thickness, optical density, modulation transfer function (MTF), and intraocular aberrations were measured.Embryonic and fetal nucleus density, lens thickness, intraocular high-order aberration (HOA), and 0.1 MTF.Embryonic, anterior, and posterior fetal nucleus densities show a positive correlation with age (P0.0001, P0.0001, and P0.0001, respectively). Lens thickness also shows a positive correlation with age (P0.0001). Total ocular and corneal HOAs for a 6-mm pupil show a positive correlation with age (P = 0.036 and P0.0001, respectively). Ocular and corneal Zernike polynomials Z4i+Z6i and intraocular spherical aberration (Z4(0)) also show a positive correlation with age (P = 0.001, P = 0.039, and P = 0.001, respectively). Intraocular coma aberration (Z3(-1)) shows a negative linear correlation with age (P0.0001). In addition, 0.1 MTF decreased with age from 18.557 to 10.100 cycles per degree.There is a degradation of the optical quality of the crystalline lens with aging that is associated with morphological changes (thickness and density). These results are important for the consideration of lens replacement in the absence of evident cataract. |
| Databáze: | OpenAIRE |
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