Predictive Values of Systemic Inflammation Index in Prognosis of Patients with Laryngeal Cancer
| Autor: | Mehmet Surmeli, Atakan Demir, Ozkan Alan |
|---|---|
| Přispěvatelé: | Acibadem University Dspace |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Oncogene business.industry Colorectal cancer Cancer medicine.disease Systemic inflammation Gastroenterology Molecular medicine Predictive value Breast cancer Oncology Internal medicine systemic inflammation index Internal Medicine Medicine laryngeal cancer prognosis medicine.symptom business Lung cancer Disease free survival |
| Popis: | Objectives: Laryngeal cancer is the most common cancer in head and neck cancer group, of which it constitutes 75\%. Squamous cell carcinoma (SCC) is the most common histological subtype. Systemic or local inflammation is a well known promotor for cancer development and progression. Systemic immune inflammation index (S II) has been reported as an independent prognostic parameter in various cancers. We aimed to evaluate the capability of SII in predicting the risk of recurrence in patients with operable laryngeal cancer. Methods: We retrospectively collected the data of 100 laryngeal SCC patients who underwent surgery between 2016 and 2018. Neutrophil, lymphocyte, and platelet (Plt) counts were recorded. The SII was calculated as follows: SII= Neutrophile counts {*}platelet counts/lymphocyte counts. Results: SI index was found to be an independent prognostic factor as affecting disease recurrence (p891 had a risk of disease recurrence of approximately three times more than patients with SII = |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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