Hereditary angioedema without deficiency of C1 inhibitor: response to therapy
| Autor: | Ana Karolinne Burlamaqui Melo, Aline Lury Aoki, Rosemeire Navickas Constantino-Silva, Sandra Mitie Ueda Palma, Vivian Alves Costa, Fabiane Milena Castro Araújo Pimenta, Neusa Falbo Wandalsen, Anete Sevciovic Grumach |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Pulmonary and Respiratory Medicine
Danazol medicine.medical_specialty Allergy biology Response to therapy business.industry Immunology medicine.disease Bioinformatics Gastroenterology C1-inhibitor chemistry.chemical_compound chemistry Icatibant Internal medicine Hereditary angioedema Meeting Abstract biology.protein Medicine Immunology and Allergy Fresh frozen plasma business Tranexamic acid medicine.drug |
| Zdroj: | The World Allergy Organization Journal |
| ISSN: | 1939-4551 |
| Popis: | Results Nineteen patients have been identified (2M:17F; 20-60 years old). The following therapies were oriented: combined contraceptive substitution for progestagen (10/19); treatment with progestagen (2/19); tranexamic acid (15/19): 1250mg (2), 1000mg (1), 750 (5), 500 mg (4), 250 mg (1); oxandrolon (5/19) (0.5 mg-5mg/day), danazol 200mg/day (1/19) and combined therapy woth oxandrolon and tranexamic acid in two patients. Icatibant was used in seven patients with clinical improvement. One of them reported increasing frequency of attacks after repeated use of this drug. Two patients received fresh frozen plasma during attacks with clinical improvement. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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