Figure S4 from Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner

Autor: Hans Christian Reinhardt, Sven Perner, David Maintz, Thorsten Persigehl, Jürgen Thomale, Björn Schumacher, Reinhard Büttner, Jürgen Wolf, Martin Erkel, Michael Nowak, Mehmet Deniz Akyuz, Daniela Welcker, Alexandra Florin, Luka Ozretić, Sebastian Michels, Maike Wittersheim, Arina Riabinska, Anna Schmitt, Christian Fritz, Christiane Kümpers, Anne Offermann, Wenzel Vogel, Judith Spiro, Niklas Klümper, Miriam Rinneburger, Ignacija Vlašić, Mladen Jokić
Rok vydání: 2023
Popis: S4. (a) Representative immunostaining of Pt-(GpG) adducts in KP and KPE cell lines after cisplatin exposure (left). Quantification of Pt-(GpG) adduct staining in KP (n = 5) and KPE (n = 6) cells after cisplatin exposure (right). P values were calculated using two-tailed t-test. (b) Clonogenic survival assay of mock-treated KP and cisplatin-treated KP cells, mock-treated KPE and cisplatin-treated KPE cells, mock-treated KPE post cis and cisplatin-treated KPE post cis cells, mock-treated KPE post cis clone 6 (*6) and cisplatin-treated KPE post cis clone 6 (*6). (c) Detailed representation of Fig. 4c.
Databáze: OpenAIRE