Dermatopathia pigmentosa reticularis: A report of a case with delayed onset alopecia and onychodystrophy
| Autor: | Khalil I. Al-Hamdi, Dooha Khaleel Ismael, Anwar Qais Saadoon |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Ectodermal dysplasia
medicine.medical_specialty Case Report Dermatology noncicatricial alopecia onychodystrophy 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Adermatoglyphia Onychodystrophy medicine Reticulate hyperpigmentation dermatopathia pigmentosa reticularis reticulate hyperpigmentation integumentary system business.industry Hyperhidrosis Genodermatosis medicine.disease 030220 oncology & carcinogenesis adermatoglyphia medicine.symptom Dermatopathia pigmentosa reticularis business genodermatosis Dyskeratosis congenita |
| Zdroj: | JAAD Case Reports |
| ISSN: | 2352-5126 |
| DOI: | 10.1016/j.jdcr.2019.02.014 |
| Popis: | Dermatopathia pigmentosa reticularis (DPR) is an extremely rare autosomal dominant ectodermal dysplasia that occurs because of mutations in KRT14. It mainly affects the skin, nails, and hair, with a characteristic diagnostic triad of widespread reticulate hyperpigmentation that begins at birth or during early childhood, noncicatricial alopecia (usually mild), and onychodystrophy. Patients with this syndrome may also have adermatoglyphia, palmoplantar hyperkeratosis, hyperhidrosis or hypohidrosis, and acral dorsal nonscarring blisters.1, 2, 3, 4, 5 The first cases of DPR were reported and described in 1958 by Hauss and Oberste-Lehn.1, 6 To date |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|